Wilson, Peter, Gurusamy, Kurinchi S., Morley, Richard, Whiting, Caroline, Maeso, Beccy, FitzGerald, Graham, Bennett, Susan, Bostock, Jennifer, Brealey, David, Cann, Maria, Kiernan, Martin ORCID: https://orcid.org/0000-0001-9926-7781, Leaper, David, Moore, Michael, Oppenheim, Beryl, Thompson, Patrick and Tingle, Alison (2019) Top research priorities in healthcare-associated infection in the UK. Journal of Hospital Infection, 103 (4). pp. 382-387. ISSN 0195-6701

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Abstract

Background
There is a mismatch between research questions which are considered to be important by patients, carers and healthcare professionals and the research performed in many fields of medicine. No relevant studies which have assessed research priorities in healthcare-associated infection (HCAI) that have involved patients' and carers' opinions were identified in the literature.

Aim
The Healthcare-Associated Infections Priority Setting Partnership was established to identify the top research priorities in the prevention, diagnosis and treatment of HCAI in the UK, considering the opinions of all these groups.

Methods
The methods broadly followed the principles of the James Lind Alliance (JLA) priority setting activity.

Findings
In total, 259 unique valid research questions were identified from 221 valid responses to a consultation of patients, carers and healthcare professionals after seeking their opinions for research priorities. The steering committee of the priority setting partnership rationalized these to 50 unique questions. A literature review established that for these questions there were no recent high-quality systematic reviews, high-quality systematic reviews which concluded that further studies were necessary, or the steering committee considered that further research was required despite the conclusions of recent systematic reviews. An interim survey ranked the 50 questions, and the 10 main research priorities were identified from the top 32 questions by consensus at a final priority setting workshop of patients, carers and healthcare professionals using group discussions.

Conclusions
A priority setting process using JLA methods and principles involving patients, carers and healthcare professionals was used to identify the top 10 priority areas for research related to HCAI. Basic, translational, clinical and public health research would be required to address these uncertainties.

Item Type:	Article
Identifier:	10.1016/j.jhin.2019.08.013
Keywords:	Healthcare-associated infections, Research priorities, Antibiotic resistance, Antimicrobial resistance, Point-of-care testing
Subjects:	Medicine and health > Health promotion and public health Medicine and health > Health promotion and public health > Infection prevention
Related URLs:	Publisher Publisher
Depositing User:	Martin Kiernan
Date Deposited:	08 Feb 2022 10:44
Last Modified:	04 Nov 2024 11:31
URI:	https://repository.uwl.ac.uk/id/eprint/8777

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