Hughes, John G. ORCID: https://orcid.org/0000-0002-4513-2395, Leydon, GM, Watts, S, Hughes, S, Brindle, LA, Arden-Close, E, Bacon, R, Birch, B, Carballo, L, Plant, H, Moore, CM, Stuart, B, Yao, G, Lewith, G and Richardson, A (2020) A feasibility study of a psycho‐educational support intervention for men with prostate cancer on active surveillance. Cancer Reports, 3 (2).

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Abstract

Background: PROACTIVE is a psycho-educational support intervention for prostate cancer patients managed on Active Surveillance. PROACTIVE is comprised of two interdependent components: group workshops and internet delivered information modules. We conducted a feasibility study to determine the practicality of delivering PROACTIVE at two prostate cancer centres.

Methods: The feasibility study was a mixed methods randomized parallel-group exploratory trial. Participants were randomised using a ratio of 3:1 PROACTIVE group to treatment as usual. Qualitative semi-structured interviews and quantitative measures were completed at baseline, intervention completion (week 6), and at 6-months follow-up. Interview transcripts were analysed thematically using Framework analysis. Descriptive statistics were used to examine recruitment and retention rates, and changing trends in outcome measures.

Results: Most aspects of the research design and PROACTIVE intervention were acceptable to those participating in the study. In particular participants valued the opportunity to share and discuss experiences with other prostate cancer patients on Active Surveillance, and receive detailed authoritative information. However, three issues were identified:
1. a low response rate (13 participants recruited, response rate 16%)
2. low utilisation of internet delivered information modules
3. self-perceived low levels of anxiety amongst participants with the majority perceiving their cancer as not impacting on their day-to-day life or causing anxiety.

Conclusions: Due to these significant research design issues it is not recommended PROACTIVE be evaluated in a large scale randomised controlled trial. Further research is required to explore the impact of Active Surveillance on anxiety amongst men with localized prostate cancer managed by Active Surveillance.

Item Type:	Article
Identifier:	10.1002/cnr2.1230
Additional Information:	This is the peer reviewed version of the following article: [Hughes, JG, Leydon, GM, Watts, S, et al. A feasibility study of a psycho‐educational support intervention for men with prostate cancer on active surveillance. Cancer Reports. 2020; 3:e1230. https://doi.org/10.1002/cnr2.1230], which has been published in final form at: https://doi.org/10.1002/cnr2.1230. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
Keywords:	Active Surveillance, anxiety, feasibility study, prostate cancer, psycho‐educational support
Subjects:	Medicine and health
Related URLs:	Publisher
Depositing User:	John G. Hughes
Date Deposited:	24 Oct 2020 19:07
Last Modified:	04 Nov 2024 11:46
URI:	https://repository.uwl.ac.uk/id/eprint/7392

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