Effect of short-term administration of cinnamon on blood pressure in patients with prediabetes and type 2 diabetes

Akilen, Raj, Pimlott, Zeller, Tsiami, Amalia A. and Robinson, Nicola (2013) Effect of short-term administration of cinnamon on blood pressure in patients with prediabetes and type 2 diabetes. Nutrition, 29 (10). pp. 1192-1196. ISSN 0899-9007

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Abstract

Objective

The aim of this study was to systematically review and evaluate the effect of short-term administration of cinnamon on blood pressure regulation in patients with prediabetes and type 2 diabetes by performing a meta-analysis of randomized, placebo-controlled clinical trials.

Methods

Medical literature for randomized controlled trials (RCTs) of the effect of cinnamon on blood pressure was systematically searched; three original articles published between January 2000 and September 2012 were identified from the MEDLINE database and a hand search of the reference lists of the articles obtained through MEDLINE. The search terms included cinnamon or blood pressure or systolic blood pressure (SBP) or diastolic blood pressure (DBP) or diabetes. A random effects model was used to calculate weighted mean difference and 95% confidence intervals (CI).

Results

The pooled estimate of the effect of cinnamon intake on SBP and DBP demonstrated that the use of cinnamon significantly decreased SBP and DBP by 5.39 mm Hg (95% CI, –6.89 to –3.89) and 2.6 mm Hg (95% CI, –4.53 to –0.66) respectively.

Conclusion

Consumption of cinnamon (short term) is associated with a notable reduction in SBP and DBP. Although cinnamon shows hopeful effects on BP-lowering potential, it would be premature to recommend cinnamon for BP control because of the limited number of studies available. Thus, undoubtedly a long-term, adequately powered RCT involving a larger number of patients is needed to appraise the clinical potential of cinnamon on BP control among patients with type 2 diabetes mellitus.

Item Type: Article
Uncontrolled Keywords: Blood pressure; Diabetes; Cinnamon; Blood glucose; Randomized control trials
Subjects: Medicine and health > Clinical medicine
Medicine and health > Nutrition
Depositing User: Rod Pow
Date Deposited: 19 May 2015 09:44
Last Modified: 19 Apr 2017 09:14
URI: http://repository.uwl.ac.uk/id/eprint/1215

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