Cognitive–behavioural therapy for anxiety in dementia: pilot randomised controlled trial

Spector, Aimee, Charlesworth, Georgina, King, Michael, Lattimer, Miles, Sadek, Susan, Marston, Louise, Rehill, Amritpal, Hoe, Juanita ORCID:, Qazi, Afifa, Knapp, Martin and Orrell, Martin (2015) Cognitive–behavioural therapy for anxiety in dementia: pilot randomised controlled trial. British Journal of Psychiatry, 206 (6). pp. 509-516. ISSN 0007-1250

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Anxiety is common and problematic in dementia, yet there is a lack of effective treatments.

To develop a cognitive–behavioural therapy (CBT) manual for anxiety in dementia and determine its feasibility through a randomised controlled trial.

A ten-session CBT manual was developed. Participants with dementia and anxiety (and their carers) were randomly allocated to CBT plus treatment as usual (TAU) (n = 25) or TAU (n = 25). Outcome and cost measures were administered at baseline, 15 weeks and 6 months.

At 15 weeks, there was an adjusted difference in anxiety (using the Rating Anxiety in Dementia scale) of (–3.10, 95% CI −6.55 to 0.34) for CBT compared with TAU, which just fell short of statistical significance. There were significant improvements in depression at 15 weeks after adjustment (–5.37, 95% CI −9.50 to −1.25). Improvements remained significant at 6 months. CBT was cost neutral.

CBT was feasible (in terms of recruitment, acceptability and attrition) and effective. A fully powered RCT is now required.

Item Type: Article
Identifier: 10.1192/bjp.bp.113.140087
Additional Information: This article has been published in a revised form in British Journal of Psychiatry This version is free to view and download for private research and study only. Not for re-distribution or re-use. © Royal College of Psychiatrists, 2015.
Subjects: Medicine and health > Clinical medicine > Dementia
Related URLs:
Depositing User: Juanita Hoe
Date Deposited: 10 Nov 2021 13:59
Last Modified: 06 Feb 2024 16:07


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