Healthy volunteering and phase I clinical drug trials in the UK

Mwale, Shadreck ORCID: (2017) Healthy volunteering and phase I clinical drug trials in the UK. In: Healthy Volunteers in Commercial Clinical Drug Trials. Palgrave Macmillan, Springer, pp. 1-24. ISBN 9783319592145

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This chapter introduces the rationale, context, and main themes of the book. It explores what clinical drug trials are and why a sociological analysis of human involvement is important. It provides a context of human involvement in clinical drug trials; this includes a discussion on the history of human involvement and interrogation of the volunteer as a concept. This chapter charts the changes to regulatory frameworks and how they brought about the shift from the use of captive populations to ‘volunteers’ capable of rational consent. It also includes a discussion on the commercial contexts in which clinical drug trials take place today.

Item Type: Book Section
Identifier: 10.1007/978-3-319-59214-5_1
Keywords: Clinical drug trials, Healthy volunteers, Volunteering, Phase I
Subjects: Medicine and health > Clinical medicine
Medicine and health
Related URLs:
Depositing User: Shadreck Mwale
Date Deposited: 03 Dec 2021 11:12
Last Modified: 03 Dec 2021 11:12

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