Atopic manifestations in the acquired immune deficiency syndrome: response to recombinant interferon gamma

Parkin, J. M., Eales-Reynolds, Lesley-Jane ORCID: 0000-0002-9906-2484, Galazka, A. R. and Pinching, A. J. (1987) Atopic manifestations in the acquired immune deficiency syndrome: response to recombinant interferon gamma. British Medical Journal (Clinical research ed.), 294 (6581). pp. 1185-1186. ISSN 0267-0623

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Abstract

Six patients with the acquired immune deficiency syndrome (AIDS) had exacerbations or recurrences of previously quiescent atopic disease when they developed immunodeficiency. Four developed a different atopic illness from that suffered previously. Atopic symptoms developed within three months after the patients developed AIDS or during prodromal illness. Two of the patients were treated with recombinant interferon gamma: both showed a striking improvement in symptoms and cellular immunity. These results indicate that cellular immunity, through interferon gamma, may have a role in regulating atopic disease.

Item Type: Article
Uncontrolled Keywords: Male, Humans, Interferon-gamma, Acquired Immunodeficiency Syndrome, Adult, Female, Hypersensitivity, Immediate, Immunity, Cellular, Middle Aged, Recombinant Proteins, Recurrence
Subjects: Medicine and health
Depositing User: Lesley-Jane Eales-Reynolds
Date Deposited: 20 May 2018 08:20
Last Modified: 21 May 2018 11:36
URI: http://repository.uwl.ac.uk/id/eprint/5060

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