HOX genes in high grade ovarian cancer

Idaikkadar, Praveena, Morgan, Richard ORCID: https://orcid.org/0000-0002-8721-4479 and Michael, Agnieszka (2019) HOX genes in high grade ovarian cancer. Cancers, 11 (8). p. 1107. ISSN 2072-6694

[img]
Preview
PDF
HOX genes in high grade ovarian ca 2019.pdf - Published Version
Available under License Creative Commons Attribution.

Download (379kB) | Preview

Abstract

HOX genes are highly conserved members of the homeobox superfamily that have a crucial role in determining cellular identity. High grade ovarian cancer is the most lethal gynaecological malignancy. Our understanding of the role of HOX genes in the oncogenesis of ovarian cancer is evolving, and here we review their dysregulated expression patterns, their function in cell survival and invasion, their potential uses as biomarkers, and ways in which HOX genes are being targeted with new and existing drugs

Item Type: Article
Uncontrolled Keywords: HOX; ovarian cancer
Subjects: Natural sciences > Cell and molecular biology
Related URLs:
Depositing User: Richard Morgan
Date Deposited: 08 Jul 2020 09:22
Last Modified: 08 Jul 2020 13:30
URI: http://repository.uwl.ac.uk/id/eprint/7097

Downloads

Downloads per month over past year

Actions (login required)

View Item View Item

Menu