HOX genes in high grade ovarian cancer

Idaikkadar, Praveena, Morgan, Richard ORCID: https://orcid.org/0000-0002-8721-4479 and Michael, Agnieszka (2019) HOX genes in high grade ovarian cancer. Cancers, 11 (8). p. 1107. ISSN 2072-6694

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HOX genes are highly conserved members of the homeobox superfamily that have a crucial role in determining cellular identity. High grade ovarian cancer is the most lethal gynaecological malignancy. Our understanding of the role of HOX genes in the oncogenesis of ovarian cancer is evolving, and here we review their dysregulated expression patterns, their function in cell survival and invasion, their potential uses as biomarkers, and ways in which HOX genes are being targeted with new and existing drugs

Item Type: Article
Identifier: 10.3390/cancers11081107
Keywords: HOX; ovarian cancer
Subjects: Natural sciences > Cell and molecular biology
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Depositing User: Richard Morgan
Date Deposited: 08 Jul 2020 09:22
Last Modified: 06 Feb 2024 16:03
URI: https://repository.uwl.ac.uk/id/eprint/7097


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