Electro-encephalogram-based indices applied to dogs’ depth of anaesthesia monitoring

Bras, S., Georgakis, Apostolos, Ribeiro, L., Ferreira, D.A., Silva, A., Antunes, L. and Nunes, C.S. (2014) Electro-encephalogram-based indices applied to dogs’ depth of anaesthesia monitoring. Research in Veterinary Science, 97 (3). pp. 597-604. ISSN 0034-5288

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Abstract

Hypnotic drug administration causes alterations in the electroencephalogram (EEG) in a dose-dependent manner. These changes cannot be identified easily in the raw EEG, therefore EEG based indices were adopted for assessing depth of anaesthesia (DoA). This study examines several indices for estimating dogs' DoA.

Data (EEG, clinical end-points) were collected from 8 dogs anaesthetized with propofol.

EEG was initially collected without propofol. Then, 100 ml h−1 (1000 mg h−1) of propofol 1% infusion rate was administered until a deep anaesthetic stage was reached. The infusion rate was temporarily increased to 200 ml h−1 (2000 mg h−1) to achieve 80% of burst suppression.

The index performance was accessed by correlation coefficient with the propofol concentrations, and prediction probability with the anaesthetic clinical end-points. The temporal entropy and the averaged instantaneous frequency were the best indices because they exhibit: (a) strong correlations with propofol concentrations, (b) high probabilities of predicting anaesthesia clinical end-points.

Item Type: Article
Subjects: Construction and engineering > Digital signal processing
Depositing User: Apostolos Georgakis
Date Deposited: 04 Jul 2018 16:56
Last Modified: 10 Jul 2018 11:24
URI: http://repository.uwl.ac.uk/id/eprint/5275

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