Intestinal protozoan and helminthic infections among hemodialysis and cancer patients

Mahmoudi, Mohammad Reza, Hasani, Hoseyin, Tsiami, Amalia ORCID: https://orcid.org/0000-0002-1122-4814, Ashrafi, Keyhan, Johnson, Paul, Sharifdini, Mysam and Karanis, Panagiotis (2020) Intestinal protozoan and helminthic infections among hemodialysis and cancer patients. Parasitology Research. ISSN 0932-0113

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Abstract

Intestinal parasitic infections (IPIs) can be a severe threat to immunocompromised patients. This is particularly true for those undergoing chemotherapy and hemodialysis. The present research is aimed at identifying intestinal parasites that might be present
in immunocompromised patients. In this cross-sectional study 1040 stool samples were collected (279 samples from hemodialysis patients, 362 samples from chemotherapy patients and 399 samples from the control group) from March to September 2017. The samples were tested by direct, formalin-ether methods for protozoa and ova of intestinal parasites and Ziehl-Neelsen staining methods for coccidian parasites such as Cryptosporidium species. The overall parasitic infection rate was higher (15%) in hemodialysis patients and 11.3% in chemotherapy patients
whereas the lowest rate was observed (7.3%) in the control group. The infectivity rates were statistically significant (P = 0.008) when compared with the control group. The most prevalent parasites present were Blastocystis hominis (8.9% of the cases), Entamoeba coli (1.6%), Iodamoeba butschlii (0.8%), Endolimax nana (0.6%), Chilomastix mesnili (0.5%), Strongyloides stercoralis (0.5%) and Taenia species (0.15%), whereas Giardia lamblia was found present only in the control group. Statistical analyses revealed a significant correlation between gastrointestinal symptoms (such as some abdominal pain, diarrhea) and the ratio of chemotherapy frequency to scheduled frequency and parasitic infections (P = 0.001). There was not a correlation between prevalence of parasites with age or education levels of the infected individuals. Results of the present study suggest that a periodic stool examinations in special parasitological laboratories should be included as part of routine and general medical care.

Item Type: Article
Additional Information: This is a post-peer-review, pre-copyedit version of an article published in Parasitology Research. The final authenticated version is available online at: https://doi.org/10.1007/s00436-020-06774-5
Uncontrolled Keywords: Parasites, Dialysis, Chemotherapy, Prevalence, Iran
Subjects: Medicine and health > Health promotion and public health
Related URLs:
Depositing User: Amalia Tsiami
Date Deposited: 16 Jun 2020 14:16
Last Modified: 24 Jul 2020 09:17
URI: http://repository.uwl.ac.uk/id/eprint/7042

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